A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/47 (2006.01) C12N 9/26 (2006.01)
Patent
CA 2296581
The use of hyaluronidase in the manufacturing of a drug for the treatment of conditions of inflammation associated with an increased local synthesis of hyaluronan in a mammal, e.g. in connection with organ grafting. The drug comprises hyaluronidase in an amount giving a daily dosage of from 1 to 20 000 IU/kg body weight when given locally or systemically to a mammal. A method of treating inflammatory conditions associated with an increased local synthesis of hyaluronan by systemic or local treatment with a pharmaceutical comprising hyaluronidase.
L'invention concerne l'utilisation de la hyaluronidase dans la production d'un médicament destiné au traitement d'états inflammatoires associés à une augmentation de la synthèse locale d'hyaluronan chez un mammifère, p.ex. en relation avec une greffe d'organe. Le médicament comprend de la hyaluronidase dans une quantité donnant un dosage quotidien de 1 à 20 000 IU/kg de masse corporelle en cas d'administration locale ou systématique chez un mammifère. Un procédé permettant de traiter des états inflammatoires associés à une augmentation de la synthèse locale de hyaluronan fait appel à un traitement local ou systémique par un médicament contenant de la hyaluronidase.
Gerdin Bengt
Hallgren Roger
Johnsson Cecilia
Tufveson Gunnar
Gerdin Bengt
Hallgren Roger
Johnsson Cecilia
Linc Invest Ab
Smart & Biggar
LandOfFree
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