Use of hydrophobic zeolites, syringe and method for removing...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 1/14 (2006.01) A61K 38/00 (2006.01) A61M 5/165 (2006.01) A61M 5/31 (2006.01) B01D 15/00 (2006.01) B01J 20/16 (2006.01) C07K 1/34 (2006.01) C07K 14/61 (2006.01) C07K 14/62 (2006.01)

Patent

CA 2235767

A new use of hydrophobic zeolites, viz. for removing preservatives from (poly)peptide solutions, e.g. solutions of pharmaceutical preparations. The use is of particular interest in connection with protein solutions, especially insulin solutions. The invention further relates to an injection syringe for such solutions, in which syringe a zeolite of the type at issue is placed for contact with the solution to remove preservatives therefrom.

L'invention concerne une nouvelle utilisation de zéolites hydrophobes, qui consiste à éliminer les conservateurs des solutions de (poly)peptides, par exemple des solutions de préparations pharmaceutiques. Cette utilisation est particulièrement intéressante pour les solutions de protéines, notamment d'insuline. L'invention concerne en outre une seringue d'injection pour ces solutions, dans laquelle un zéolite du type en question est mis en contact avec la solution afin d'en éliminer les conservateurs.

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