Use of hydroxyoleic acid and related compounds in the...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/20 (2006.01) A61K 31/19 (2006.01) A61K 31/198 (2006.01) A61K 31/201 (2006.01) A61P 3/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2463348

The invention relates to the use of hydroxyoleic acid and similar compounds having general formula I: COOH-CHR-(CH2)m-CH=CH-(CH2)n-CH3, wherein m and n independently represent a value of between 0 and 15 and R can denote any residue having a molecular mass of less than 200 Da. The invention relates to the use of said hydroxyoleic acid and similar compounds in the production of medicaments that are used to treat cancer, hypertension, obesity or diseases caused by an alteration of the membrane structure and the resulting regulation of G proteins or the receptors connected to same.

L'invention porte sur l'utilisation de l'acide hydroxy-oléique et de ses composés analogues dans la fabrication de médicaments. L'invention vise à décrire l'utilisation de l'acide hydroxy-oléique et de ses analogues de formule générale I: COOH-CHR-(CH2)m-CH=CH-(CH2)n-CH3, dans laquelle m et n représentent, indépendamment, une valeur comprise entre 0 et 15 et R peut désigner un quelconque résidu dans la masse moléculaire est inférieure à 200 Da. L'invention permet la fabrication de médicaments utiles dans le traitement du cancer, l'hypertension, l'obésité ou des maladies induites par l'altération de la structure membranaire et la régulation de protéines G ou des récepteurs couplés auxdites protéines.

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