Use of ifn-alpha and amantadine for the treatment of chronic...

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61K 38/21 (2006.01)

Patent

CA 2302834

The present invention provides the use of IFN-.alpha. in association with Amantadine for the manufacture of medicaments for the treatment of chronic hepatitis C infections. The present invention also provides medicaments containing the IFN-.alpha. and Amantadine as a combined preparation for simultaneous, separate or sequential use in therapy of chronic hepatitis C infections. The present invention further provides a method for treating chronic hepatitis C infections in patients in need of such treating comprising administering an amount of IFN-.alpha. in association with an amount of Amantadine effective to treat hepatitis C.

La présente invention concerne l'utilisation d'interféron-alpha (IFN-.alpha.) associé à l'amantadine, dans la fabrication de médicaments destinés au traitement d'infections par le virus de l'hépatite C chronique, et elle concerne également des médicaments contenant l'IFN-.alpha. et l'amantadine en tant que préparation combinée destinée à un emploi simultané, séparé ou séquentiel dans la thérapie d'infections par le virus de l'hépatite C chronique. L'invention concerne encore une méthode de traitement de telles infections chez des patients nécessitant un tel traitement, cette méthode consistant à administrer une dose d'IFN-.alpha. associée à une dose d'amantadine qui soit efficace pour traiter l'hépatite C.

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