Use of il-1 inhibitors and tnf antagonists, partially in...

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 7/06 (2006.01)

Patent

CA 2425842

The invention relates to methods of treating a blood disorder in a mammal with an interleukin-1 (IL-1) inhibitor. The invention also relates to methods of treating a blood disorder in a mammal with an IL-1 inhibitor, a TNF inhibitor and an erythropoietin (EPO) receptor agonist. The invention also relates to compositions of an IL-1 inhibitor and compositions of an IL-1 inhibitor, a TNF inhibitor and an EPO receptor agonist.

La présente invention concerne des procédés permettant de traiter une maladie du sang chez un mammifère avec un inhibiteur d'interleukine-1 (IL-1); des procédés de traitement d'une maladie du sang chez un mammifère avec un inhibiteur IL-1, un inhibiteur du facteur de croissance des tumeurs (TNF) et un agoniste du récepteur des érythropoïétines (EPO); des compositions d'un inhibiteur IL-1 et des compositions d'un inhibiteur IL-1, d'un inhibiteur TNF et d'un agoniste du récepteur EPO.

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