Use of il-18 inhibitors

Details Use of il-18 inhibitors Use of il-18 inhibitors

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/00 (2006.01) A61K 35/12 (2006.01) A61K 38/17 (2006.01) A61K 38/21 (2006.01) A61K 48/00 (2006.01) A61P 1/04 (2006.01) A61P 1/16 (2006.01) A61P 19/02 (2006.01) A61P 37/02 (2006.01) C07K 16/24 (2006.01) C12N 15/63 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2399298

The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of liver injury. The invention further relates to the use of IL-18 inhibitors in the preparation of a medicament for treatment and/or prevention of arthritis, in particular rheumatoid arthritis. In addition to this, the invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of inflammatory bowel diseases, in particular of Crohn's disease and ulcerative colitis.

L'invention concerne l'utilisation d'inhibiteurs de IL-18 dans la préparation d'un médicament destiné au traitement et/ou à la prévention d'une lésion hépatique. L'invention concerne également l'utilisation d'inhibiteurs de IL-18 dans la préparation d'un médicament destiné au traitement et/ou à la prévention de l'arthrite, notamment l'arthrite rhumatoïde, ainsi que de maladies inflammatoires intestinales, notamment la maladie de Crohn et la colite ulcéreuse.

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