Use of il-18 inhibitors for the treatment and/or prevention...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) C07K 14/47 (2006.01) C07K 14/54 (2006.01) C07K 14/715 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2435466

The invention relates to the use of an inhibitor of IL-18 in the preparation of a medicament for treatment and/or prevention of a heart disease, in particular ischemic heart disease. Combinations of an IL-18 inhibitor and/or a TNF antagonist are also considered for the treatment and/or prevention of a heart disease.

L'invention concerne l'utilisation d'un inhibiteur d'IL-18 dans la préparation d'un médicament destiné au traitement et/ou à la prévention d'une cardiopathie, en particulier d'une cardiopathie ischémique. Des combinaisons d'un inhibiteur d'IL-18 et/ou d'un antagoniste du TNF sont également prises en considération pour le traitement et/ou la prévention d'une cardiopathie.

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