Use of il-18bp isoforms for the treatment and/or prevention...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 25/00 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2610691

The invention relates to the use of an IL18-BP isoform that does not bind to IL18, or of an agonist thereof, for treatment or prevention of a neurological and/or inflammatory disease. Preferred isoforms for use in the frame of the present invention include IL-18BPb and IL-18BPd.

L'invention concerne l'utilisation d'un isoforme d'IL18-BP qui ne se lie pas à IL18, ou d'un agoniste de celui-ci, dans le traitement ou la prévention d'une maladie neurologique et/ou inflammatoire. Les isoformes préférés selon l'invention comprennent IL-18BPb et IL-18BPd.

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