Use of il-6 antagonists in combination with steroids to...

Details Use of il-6 antagonists in combination with steroids to... Use of il-6 antagonists in combination with steroids to...

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01) A61K 31/573 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2514997

Methods for the use of antibodies directed toward IL-6, including specified portions or variants, specific for at least one Interleukin-6 (IL-6 also known as interferon .szlig.2)) protein or fragment thereof, in combination with steroids for the treatment of proliferative diseases such as cancer which are amenable to treatment by apoptosis inducing agents.

L'invention concerne des procédés d'utilisation d'anticorps dirigés contre IL-6, y compris des portions ou des variants spécifiés, spécifiques d'au moins une interleukine-6 (IL-6, connu également sous le nom d'interféron .beta.2), une protéine ou fragment de ceux-ci, en combinaison avec des stéroïdes pour le traitement de maladies proliférantes, telles que le cancer, relevant du traitement par des agents provoquant l'apoptose.

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