Use of indazole derivatives for the treatment of neuropathic...

A - Human Necessities – 61 – K

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A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61P 25/02 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2526052

Use of a compound of formula (I), wherein X is CH or N, and when X is CH, R is H, OH, a linear or branched alkyl chain having from 1 to 3 carbon atoms, a linear or branched alkoxy chain having from 1 to 3 carbon atoms, or a halogen atom, and when X is N, R is H, or an acid addition salt thereof with a pharmaceutically acceptable organic or inorganic acid, to prepare a pharmaceutical composition active in the treatment of neuropathic pain.

L'invention concerne un composé de la formule (I) où X représente CH ou N. Si X représente CH, R représente H, OH, une chaîne alkyle linéaire ou ramifiée ayant de 1 à 3 atomes de carbone, une chaîne alcoxy linéaire ou ramifiée ayant 1 à 3 atomes de carbone ou un atome d'halogène mais si X représente N, R représente H ou un sel d'addition acide de ce dernier avec un acide organique ou anorganique pharmaceutiquement tolérable. L'invention concenre l'utilisationde ce composé pour préparer une composition pharmaceutique active dans le traitement des douleurs neuropathiques.

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