Use of indigestible oligosaccharides to treat and prevent...

A - Human Necessities – 61 – K

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Details

A61K 31/70 (2006.01) A23C 9/13 (2006.01) A23C 9/152 (2006.01) A23C 9/20 (2006.01) A23G 3/00 (2006.01) A23L 1/30 (2006.01) A23L 1/308 (2006.01) A23L 2/52 (2006.01) A61K 31/702 (2006.01)

Patent

CA 2226420

A method is provided for reducing the incidence of otitis media in infants and young children by enterally administering indigestible oligosaccharides. More specifically, the present invention relates to a method for reducing the incidence of otitis media comprising administering to humans an indigestible oligosaccharide selected from the group consisting of fructooligosaccharides, fructosans, xylooligosaccharides and galactooligosaccharides. The indigestible oligosaccharides can be produced through enzymatic synthesis, chemical techniques or isolated from plant materials and are administered in the form of a nutritional product, candy, tablets, chewing gums, lozenges, milk products, yogurts and the like. In a preferred embodiment of this invention, the indigestible oligosaccharides have a DP of 2 to 20 and still more preferably are the fructooligosaccharides GF2, GF3 and GF4.

L'invention concerne un procédé pour diminuer l'incidence de l'otite moyenne chez les nourrissons et les jeunes enfants, par l'administration orale d'oligosaccharides non digestibles. Plus précisément, l'invention concerne un procédé pour diminuer l'incidence de l'otite moyenne, consistant à administrer à des humains un oligosaccharide non digestible choisi dans le groupe constitué par les fructo-oligosaccharides, les fructosans, les xylo-oligosaccharides et les galacto-oligosaccharides. Les oligosaccharides non digestibles peuvent être obtenus par synthèse enzymatique, par des procédés chimiques ou isolés à partir de matières végétales et ils sont administrés par voie orale sous une forme appropriée, par exemple sous la forme de sucres d'orge, de comprimés, de chewing-gums, de pastilles, de produits laitiers, de yaourts et similaire. Dans une forme d'exécution préférée de cette invention, les oligosaccharides non digestibles ont un degré de polymérisation de 2 à 20 et, de préférence, ce sont les fructo-oligosaccharides GF¿2?, GF¿3? et GF¿4?.

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