Use of indigoid bisindole derivatives for the manufacture of...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 47/48 (2006.01) C07D 209/34 (2006.01) C07D 209/40 (2006.01)

Patent

CA 2333661

The present invention relates to the use of indigoid bisindole derivatives for the manufacture of a medicament for inhibiting cyclin dependent kinases, particularly CDK 1, CDK 2, CDK 4 and CDK 5, more particularly ATP:Proteinphosphotransferase p34cdc2 (CDK1).

L'invention concerne l'utilisation de dérivés bisindoliques d'indigoïdes afin de préparer un médicament servant à inhiber des kinases dépendantes de cycline, en particulier, CDK1, CDK2, CDK4 et CDK5, plus particulièrement ATP :protéine phosphotransférase p34?cdc2¿ (CDK1).

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