Use of indolyl-3-glyoxylic acid derivatives including...

A - Human Necessities – 61 – K

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A61K 31/404 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2670778

The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin.

Cette invention concerne un traitement combiné, dans lequel un ou plusieurs autres agents thérapeutiques sont administrés avec l'indibuline ou un sel de l'indibuline pharmaceutiquement acceptable, cette combinaison étant synergique. L'invention concerne également le traitement du cancer avec utilisation de l'indibuline comme agent unique. L'invention concerne par ailleurs le schéma posologique pour l'administration de formes pharmaceutiques orales d'indibuline.

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