Use of inhibitors of heparin-binding epidermal growth factor...

A - Human Necessities – 61 – K

Patent

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A61K 31/00 (2006.01) A61K 31/56 (2006.01) A61K 31/727 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61K 39/05 (2006.01) A61K 39/395 (2006.01) A61K 45/06 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2459071

The invention concerns the use of at least an inhibitor of the heparin-binding epidermal growth factor or at least an inhibitor of the HB-EGF receptors, or ErbB receptors, or of at least an inhibitor of associated transduction pathways for preparing medicines useful for treating apoptosis and/or inhibiting IL-6 dependent plasmocytic tumor cell proliferation.

La présente invention a pour objet l'utilisation d'au moins un inhibiteur du facteur de croissance épidermique (EGF) liant l'héparine (HB) ou d'au moins un inhibiteur des récepteurs de HB-EGF, ou récepteurs ErbB, ou d'au moins un inhibiteur des voies de transduction associées pour la préparation de médicaments utiles pour induire l'apoptose et/ou inhiber la prolifération des cellules tumorales plasmocytaires IL-6 dépendantes.

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