Use of inhibitors of pkc for the manufacture of a medicament...

Details Use of inhibitors of pkc for the manufacture of a medicament... Use of inhibitors of pkc for the manufacture of a medicament...

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/407 (2006.01)

Patent

CA 2263499

A method for treating central nervous system associated with HIV infection is disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4- [N,N'-1,1'-((2''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-butane)-bis-(3,3'- indolyl)]-1(H)-pyrrole-2,5-dione hydrochloride salt.

Méthode de traitement du système nerveux central associé à des infections causées par le virus de l'immunodéficience humaine (HIV), notamment au moyen de l'inhibiteur protéine kinase c (PKC) à sélectivité d'isoenzyme, sel chlorhydrate de (S)-3,4-[N,N'-1,1'-((2''-éthoxy)-3'''(0)-4'''-(N,N-diméthylamino)-butane)-bis-(3,3'-indoly1)]-(H)-pyrrole-2,5-dione.

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