Use of inhibitors of steroid (testosterone) activity (i. a....

A - Human Necessities – 61 – K

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A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61P 5/00 (2006.01) A61P 25/30 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2601051

The invention concerns the use of one or more steroid activity inhibitors, wherein the steroid to be inhibited is androgen, such as, for example, testosterone, for the treatment of disorders related to, or resulting from use of, or induced by substances or induced by intoxication from substances or abstinence from substances, mental disorders induced by substances, substance addiction or gambling, abuse of substances or recurrent criminal behaviour. The steroid activity inhibitors are for instance testosterone production inhibitors <triptorelin, leuporelin, buserelin, goserelin, ketoconazole, aminoglutamide, >, testosterone activity inhibitors < estrogens or antiandrogens like bicalutamide, .sigma.ypr.sigma.terone, flutamide, danazol>, steroid transport inhibitors <mepartricin> or drugs preventing the transformation of testosterone in dihydrotestosterone <f inasteride, destasteride>

L'invention concerne l'utilisation d'un ou plusieurs inhibiteurs d'activité stéroïde, notamment des androgènes, tel que, par exemple, la testostérone, dans le traitement de troubles liés à, ou résultant de l'utilisation de, ou induit par des substances ou par intoxication par ces substances ou abstinence de ces substances, des troubles mentaux induits par celles-ci, la dépendance à ces substances, l'abus de substances ou le comportement criminel récurrent.

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