Use of inhibitors of the cellular na+/h+ exchanger (nhe) for...

A - Human Necessities – 61 – K

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A61K 31/155 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/33 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2257299

The active substances identified as inhibitors of the cellular Na+/H+ exchanger (NHE) are used to prepare a medicament for normalizing serum lipids. They are used in the preparation of a medicament which reduces lipid levels in the blood and can be administered for treating diseases caused by lipid levels which are too high, and for alleviating the endothelial dysfunctional syndrome and for treating diseases caused thereby.

Les principes actifs identifiés comme inhibiteurs de l'échangeur cellulaire Na<+>H<+> (NHE) sont utilisés pour préparer un médicament servant à normaliser les lipides sériques. Ils s'utilisent dans la préparation d'un médicament permettant d'abaisser le taux de lipides dans le sang et par conséquent de traiter les maladies induites par des taux trop élevés, et de réduire le syndrome dysfonctionnel endothélial de traiter les maladies qu'il induit.

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