Use of inhibitors of the renin-angiotensin system in the...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61K 31/00 (2006.01) A61K 31/355 (2006.01) A61K 31/403 (2006.01) A61K 31/60 (2006.01) A61K 31/616 (2006.01) A61K 45/06 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2382549

The present invention relates to the use of an inhibitor of the renin- angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin, in the manufacture of a medicament for the prevention of cardiovascular events; to a method of preventing cardiovascular events comprising administering to a patient in need of such prevention an effective amount of an inhibitor of the renin angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with an other antihypertensive, a cholesterol lowering agent, a diuretic or aspirin; or to a combination product containing an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof and a cholesterol lowering agent.

La présente invention concerne l'utilisation d'un inhibiteur du système rénine-angiotensine, ou un de ses sels acceptable sur le plan pharmaceutique, éventuellement associé avec un autre hypertenseur, un agent hypocholestérolémiant, un diurétique ou de l'aspirine, dans la fabrication d'un médicament destiné à la prévention de manifestations cardio-vasculaires. Elle concerne aussi une méthode de prévention de manifestations cardio-vasculaires qui consiste à administrer à un patient nécessitant une telle prévention une quantité efficace d'un inhibiteur du système rénine-angiotensine, ou un de ses sels acceptable sur le plan pharmaceutique, éventuellement associé avec un autre hypertenseur, un agent hypocholestérolémiant, un diurétique ou de l'aspirine, ou d'un produit d'une combinaison contenant un inhibiteur du système rénine-angiotensine, ou un de ses sels acceptable sur le plan pharmaceutique et un agent hypocholestérolémiant.

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