Use of inhibitors of toll-like receptors in the prevention...

Details Use of inhibitors of toll-like receptors in the prevention... Use of inhibitors of toll-like receptors in the prevention...

A - Human Necessities

61

K

A61K 31/7088 (2006.01) A61K 31/4706 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2738816

The invention provides the use of TLR inhibitors or a pharmaceutically acceptable derivative thereof, optionally in combination with one or more lipid lowering composition, cholesterol lowering composition, diuretics, non-steroidal anti-inflammatory compounds (NSAIDs), antibodies, antisense oligonucleotides, TLR agonists, TLR antagonists, peptides, proteins or gene therapy vectors or combinations thereof for the prevention or treatment of hypercholesterolemia and/or hyperlipidemia and/or diseases associated therewith.

Linvention a pour objet lutilisation dinhibiteurs de TLR ou de lun de leurs dérivés pharmaceutiquement acceptables, éventuellement en combinaison avec un(e) ou plusieurs dune composition hypolipidémiante, dune composition hypocholestérolémiante, de diurétiques, de composés anti-inflammatoires non stéroïdiens (AINS), danticorps, doligonucléotides antisens, dagonistes de TLR, de peptides, de protéines ou de vecteurs de génothérapie ou de combinaisons de ces substances pour la prévention ou le traitement de lhypercholestérolémie et/ou de lhyperlipidémie et/ou de maladies qui y sont associées.

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