A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/415 (2006.01) A61K 31/16 (2006.01) A61K 31/71 (1995.01)
Patent
CA 2142313
The activity of inhibitors of vacuolar type H + -ATPases in the inhibition of vacuolation induced by Helicobacter pylori is disclosed. Preferred agents are the macrolide antibiotics bafilomycins A1, A2, B1, B2, C1, C2 and D, especially bafilomycin A1. The use of such compounds in the treatment of diseases, including peptic ulceration, is claimed.
Bugnoli Massimo
Montecucco Cesare
Papini Emanuele
Rappuoli Rino
Borden Ladner Gervais Llp
Chiron S.p.a.
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