Use of interfering rna in the production of transgenic animals

Details Use of interfering rna in the production of transgenic animals Use of interfering rna in the production of transgenic animals

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/79 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2546853

The invention provides cells and animals, as well as methods of producing cells and animals, that express at least one interfering RNA molecule to regulate the expression of a specific gene or family of genes. The invention further provides novel iRNA molecules, as well as DNA templates for producing iRNA molecules.

La présente invention a trait à des cellules et des animaux, ainsi qu'à des procédés de production de cellules et d'animaux, exprimant au moins une molécule d'ARN interférence pour la régulation de l'expression d'un gène ou d'une famille de gènes spécifique. L'invention a également trait à de nouvelles molécules d'ARNi, ainsi qu'à des matrices d'ADN pour la production de molécules d'ARNi.

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