Use of interleukin 17e for the treatment of cancer

Details Use of interleukin 17e for the treatment of cancer Use of interleukin 17e for the treatment of cancer

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 31/337 (2006.01) A61K 31/4164 (2006.01) A61K 31/7088 (2006.01) A61K 35/413 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2599754

The use of interleukin 17E to inhibit tumour growth in a subject is provided. The interleukin 17E can be provided to the subject exogenously, as an interleukin 17E polypeptide or a polynucleotide encoding an interleukin 17E polypeptide, or it can be provided by stimulating production of endogenous interleukin 17E. Also provided is the use of interleukin 17E in combination with one or more anti-cancer therapeutics for inhibiting tumour growth in a subject. Anti-cancer therapeutics include, for example, standard chemotherapeutic drugs, immunotherapeutics, radiation, gene therapy, hormone manipulation and antisense therapy.

L'invention concerne l'utilisation de l'interleukine 17E pour inhiber la croissance tumorale chez un sujet. L'interleukine 17E peut être fournie au sujet par voie exogène, sous la forme d'un polypeptide d'interleukine 17E ou d'un polynucléotide codant pour un polypeptide d'interleukine 17E, ou peut être fournie par stimulation de la production d'interleukine 17E endogène. L'invention concerne également l'utilisation de l'interleukine 17E en combinaison avec un ou plusieurs agents thérapeutiques anticancéreux destinés à inhiber la croissance tumorale chez un sujet. Les agents thérapeutiques anticancéreux incluent, par exemple, des médicaments chimiothérapeutiques standard, des agents immunothérapeutiques, la radiothérapie, la thérapie génique, la manipulation hormonale et la thérapie antisens.

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