Use of interleukin-22 for the prevention and/or treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 38/20 (2006.01) C07K 14/54 (2006.01)

Patent

CA 2748392

The present invention relates to use an agent for the prevention and/or treatment of multiple organ dysfunction syndrome (MODS) or multiple organ failure (MOF) comprising interleukin-22 (IL- 22) as an effective ingredient. The present invention is applicable to prevention of or therapy for diseases from sepsis, septic shock, liver failure, to multiple organ dysfunction syndromes. More particularly, the present invention is useful for an emergency medical service, for treatment of injury caused by a traffic accident, burns, heat attacks, hypercytokinemia or severe infective diseases.

La présente invention concerne lutilisation dun agent pour la prévention et/ou le traitement du syndrome de défaillance multiviscérale ou dune insuffisance polyviscérale, comprenant de linterleukine 22 (IL-22) en tant que principe actif. La présente invention sapplique à la prévention ou au traitement de maladies de la septicémie, du choc septique, de linsuffisance hépatique aux syndromes de défaillance multiviscérale. De manière plus particulière, la présente invention est utile pour un service médical durgence, pour le traitement des lésions provoquées par un accident de la circulation, des brûlures, des crises cardiaques, dune hypercytokinémie ou de maladies infectieuses sévères.

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