C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2457579
The present invention identifies essentially all of the members of a specific group of genes that are preferentially transcribed upon the initialization of a signal transduction pathway. The present invention also discloses methods for detecting and/or quantifying the transcription of these specific genes. The present invention further discloses methods of using this information to characterize the effect of potential drugs on a cell. Solid supports comprising nucleic acids tha can hybridize with the transcripts from this specific group of genes are also described.
L'invention porte sur l'identification de la quasi totalité des éléments d'un groupe spécifique de gènes de préférence transcrites lors de la création d'un mécanisme de transduction de signaux. L'invention porte également sur des procédés de détection et/ou quantification de la transcription de ces gènes, sur des procédés d'utilisation de ces informations pour caractériser l'effet de médicaments potentiels sur une cellule et sur des supports solides composés d'acides nucléiques pouvant s'hybrider avec les transcrits de groupes spécifiques de gènes.
Sealfon Stuart
Wurmbach Elisa
Yuen Tony
Mount Sinai School Of Medicine
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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