Use of intronic rna to measure gene expression

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2516553

The invention is based on the use of intronic RNA in monitoring gene expression. Accordingly, the present invention concerns methods of gene expression profiling using intronic RNA, the expression of which correlates with the expression of corresponding exonic RNA, and diagnostic and prognostic methods based on the results of such gene expression studies.

La présente invention concerne l'utilisation d'ARN intronique pour surveiller l'expression génique. Cette invention concerne ainsi des techniques de détermination de profil d'expression de gène au moyen d'ARN intronique, l'expression de ce dernier étant corrélée avec l'expression de l'ARN exonique correspondant. Cette invention concerne aussi des techniques de diagnostic et de pronostic fondées sur les résultats de ces études d'expression de gène.

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