Use of isoxazole and crotonamide derivatives for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/06 (2006.01) A61K 31/198 (2006.01) A61K 31/275 (2006.01) A61K 31/422 (2006.01) A61K 31/44 (2006.01) C07C 255/22 (2006.01)

Patent

CA 2188228

The compound of the formula I or II (see Formula II) is suitable for the production of a pharmaceutical for the treatment of carcinomatous disorders, where R1 is (C3-C5)-cycloalkyl, (C2-C6)-alkenyl or (C2-C6)-alkynyl, R2 is CF3 , OCF3, SCF3 , OH, NO2 , halogen, benzyl, phenyl, CN or O-phenyl, R3 is (C1-C4)-alkyl, halogen or a hydrogen atom and X is a -CH group or a nitrogen atom.

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