A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/55 (2006.01) A61K 31/553 (2006.01)
Patent
CA 2258662
Disclosed herein are therapeutic methodologies utilizing a ring substituted derivative of the indolocarbazole K252a, the derivative represented by the formula (A). The compound is useful for treating peripheral neuropathies, central neuronal degeneration and cytokine overproduction. Typical diseases related to the above are peripheral neuropathy, Alzheimer's disease, Parkinson's disease and autoimmune and allergic conditions.
L'invention concerne des procédés thérapeutiques dans lesquels on utilise un dérivé de substitution de l'indolocarbazole K252a, le dérivé étant représenté par la formule (A). Le composé est utile dans le traitement des neuropathies périphériques, des dégénérescences du système nerveux central, et de l'hyperproduction de cytokines. Les maladies typiques liées à ces dernières sont la neuropathie périphérique, la maladie d'Alzheimer, la maladie de Parkinson, et les phénomènes auto-immuns et allergiques.
Aimone Lisa D.
Engber Thomas M.
Haun Forrest A.
Knight Ernest Jr.
Miller Matthew S.
Cephalon Inc.
Goudreau Gage Dubuc
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