Use of l-carnitine and derivatives for reducing ceramide...

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) A61K 31/195 (2006.01) A61K 31/205 (2006.01) A61K 31/215 (2006.01) A61K 31/221 (2006.01)

Patent

CA 2228266

The present invention provides a novel use of L-carnitine, the derivatives thereof and their pharmacologically acceptable salts in combination with antiretroviral drugs for reducing ceramide levels and enhance the activity of the aforesaid antiretroviral drugs for the therapeutic treatment of HIV-infection and AIDS.

La présente invention se rapporte à une nouvelle utilisation de la L-cartinine, de certains de ses dérivés et des sels pharmacologiquement acceptables de ces dérivés en association à des médicaments antirétrovirus dans le but de réduire les niveaux de céramides et d'accroître l'activité desdits médicaments antirétrovirus dans le cadre du traitement thérapeutique de l'infection à VIH et du SIDA.

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