Use of l-carnitine and its alkanoyl derivatives in the...

A - Human Necessities – 61 – K

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A61K 31/205 (2006.01) A61P 39/00 (2006.01) A61K 31/337 (2006.01) A61K 31/475 (2006.01) A61K 31/555 (2006.01) A61K 31/7064 (2006.01)

Patent

CA 2338638

The invention described herein relates to the use of alkanoyl L-carnitine with formula (I) where R and X- are as defined in the description, in the preparation of medicaments useful for the treatment of tumours; in particular, the invention described herein refers to combinations of alkanoyl L-carnitine and anticancer agents for the treatment of tumours with an improvement in the therapeutic index and a reduction of the side effects typical of anticancer chemotherapy.

La présente invention concerne l'utilisation de alkanoyl L-carnitine, représentés par la formule (I) dans laquelle R et X<-> sont tels que définis dans le descriptif, dans la préparation de médicaments utilisés pour le traitement des tumeurs. Cette invention concerne en particulier des associations d'alkanoyl L-carnitine et d'agent anticancéreux utilisés pour traiter les tumeurs avec une amélioration dans l'index des traitements et la diminution des effets secondaires relatifs à la chimiothérapie anticancéreuse.

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