C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 1/00 (2006.01)
Patent
CA 2517396
The present invention relates to using lectin or lectin-like molecules to promote oligomerization of a glycoprotein or an immunologically and/or biologically active complex comprising glycoproteins. In particular, the invention provides compositions of a molecular complex comprising lectin molecules and immunologically and/or biologically active molecules. Methods of making such molecular complexes and methods of use of the compositions comprising such molecular complexes for the prevention and treatment of diseases, particularly cancer and infectious diseases, and for eliciting an immune response in a subject, are also provided.
La présente invention concerne l'utilisation de lectine ou de molécules du type lectine pour promouvoir l'oligomérisation d'une glycoprotéine ou d'un complexe actif du point de vue immunologique et/ou biologique comprenant des glycoprotéines. De manière plus particulière, cette invention concerne des compositions d'un complexe moléculaire comprenant des molécules de lectine et des molécules actives du point de vue immunologique et/ou biologique. La présente invention concerne également des méthodes de préparation de tels complexes moléculaires et des méthodes d'utilisation des compositions comprenant de tels complexes moléculaires dans le cadre de la prévention et du traitement des maladies, notamment le cancer et les maladies infectieuses et pour éliciter une réponse immunitaire chez un individu.
Monks Stephen A.
Zabrecky James R.
Antigenics Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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