C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2266585
The invention relates to pharmaceutical agents containing leptin antagonists for treating Type II diabetes. One leptin antagonist is based on a murine leptin fragment and comprises amino acids 116 to 167 or 116 to 166. Methods of treating Type II diabetes are also disclosed.
L'invention concerne des agents pharmaceutiques contenant des antagonistes de la leptine pouvant être utilisés pour le traitement des diabètes non insulino-dépendants. Un antagoniste de la leptine est fondé sur un fragment de leptine murine et comprend les acides aminés 116 à 167 ou 116 à 166. L'invention concerne aussi des procédés de traitement de diabètes non insulino-dépendants.
Ertl Johann
Muller Gunter
Preibisch Gerald
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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