Use of leukemia inhibitory factor and endothelin antagonists

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 38/12 (2006.01) C07K 16/24 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2214636

A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.

On peut utiliser un antagoniste du facteur d'inhibition de la leucémie, seul ou associé à un antagoniste de l'endothéline, pour traiter une insuffisance cardiaque. On administre, à cet effet, le ou les antagonistes de façon chronique, à des doses efficaces du point de vue thérapeutiques.

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