Use of leukotriene b4 or its analogues as antiviral and...

Details Use of leukotriene b4 or its analogues as antiviral and... Use of leukotriene b4 or its analogues as antiviral and...

A - Human Necessities

61

K

A61K 31/557 (2006.01) A61K 31/00 (2006.01) A61K 31/19 (2006.01) A61K 31/52 (2006.01) A61K 31/56 (2006.01) A61K 31/675 (2006.01) A61K 31/70 (2006.01) A61K 38/19 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2244078

The present invention relates to the use of leukotriene B4 (LTB4), variants and derivatives thereof as a therapeutic agent in the treatment or prophylaxis of viral infections caused by human and animal viruses. The present invention also relates to the use of LTB4, variants and derivatives thereof as an anti-neoplastic agent in the prophylaxis and treatment of cancers induced by tumor viruses and in other neoplastic diseases. The human and animal viruses are DNA viruses, such as parvoviridae, papovaviridae, adenoviridae, herpesviridae, poxviridae and hepadnaviridae; RNA viruses, such as picomaviridae, togaviridae, orthomyxoviridae, paramyxoviridae, coronaviridae, reoviridae, oncomaviridae and filoviridae in general, and Retroviridae such as HIV-1 and HIV-2.

L'invention concerne l'utilisation du leucotriène B4 (LTB4), de variantes et de dérivés de celui-ci comme agent thérapeutique dans le traitement ou la prophylaxie d'infections virales causées par des virus d'origine humaine ou animale. La présente invention concerne également l'utilisation de LTB4, de variantes et de dérivés de celui-ci comme agent antinéoplasique pour la prophylaxie et le traitement de cancers induits par des virus causant des tumeurs et d'autres maladies néoplasiques. Les virus d'origine humaine et animale sont des virus à AND, tels que les parvoviridae, les papovaviridae, les adénoviridae, les herpesviridae, les poxvididae et les hepadnaviridae; des virus à ARN tels que, généralement, les picornaviridae, les togaviridae, les orthomyxoviridae, les paramyxoviridae, les coronaviridae, les reoviridae, les oncornaviridae et les filoviridae et, plus particulièrement, les rétroviridae tels que HIV-1 et HIV-2.

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