Use of levosimendan and beta-adrenergic receptor antagonist...

Details Use of levosimendan and beta-adrenergic receptor antagonist... Use of levosimendan and beta-adrenergic receptor antagonist...

A - Human Necessities

61

K

A61K 31/501 (2006.01) A61K 31/138 (2006.01) A61K 31/403 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 9/04 (2006.01)

Patent

CA 2450915

A combination therapy for the treatment of heart failure comprises administering a combination of levosimendan or a pharmaceutically acceptable salt thereof and a beta-adrenergic receptor antagonist to a patient. The combination synergistically reduces mortality in heart failure patients.

Cette invention concerne un polythérapie pour défaillances cardiaques consistant à administrer à un patient une combinaison de lévosimendane ou d'un sel paharmaceutiquement acceptable de lévosimendane et un antagoniste de récepteur bêta-adrénergique. Cette combinaison permet de réduire synergétiquement la mortalité chez des patients atteints de défaillances cardiaques.

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