Use of lhrh antagonists for the treatment of lower urinary...

Details Use of lhrh antagonists for the treatment of lower urinary... Use of lhrh antagonists for the treatment of lower urinary...

A - Human Necessities

61

K

A61K 38/09 (2006.01) A61K 31/403 (2006.01) A61K 31/5377 (2006.01) A61P 13/00 (2006.01) A61P 13/02 (2006.01) A61P 13/10 (2006.01)

Patent

CA 2679690

The present invention provides at least one LHRH antagonist for use in the preparation of a medicament for the treatment or prophylaxis of at least one lower urinary tract symptom in mammals, wherein the at least one lower urinary tract symptom is selected from the group consisting of: "urinary incontinence, urge incontinence, overactive bladder, idiopathic overactive bladder, neurogenic overactive bladder, detrusor overactivity, idiopathic detrusor overactivity, neurogenic detrusor overactivity" and wherein the at least one LHRH antagonist is to be administered in an intermediate dose, which does not cause chemical (hormonal) castration.

La présente invention concerne au moins un antagoniste de la LHRH destiné à être utilisé dans la préparation d'un médicament utilisé dans le traitement ou la prophylaxie d'au moins un symptôme du tractus urinaire inférieur chez les mammifères, le ou les symptômes du tractus urinaire inférieur étant choisis dans le groupe constitué par : l'incontinence urinaire, l'incontinence par impériosités, la vessie hyperactive, la vessie hyperactive idiopathique, la vessie hyperactive neurogénique, l'hyperactivité du détrusor, l'hyperactivité du détrusor idiopathique, l'hyperactivité du détrusor neurogénique ; le ou les antagonistes de la LHRH devant être administrés dans une dose intermédiaire ne provoquant pas de castration chimique (hormonale).

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