Use of lignan derivatives for the preparation of...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) C07H 17/04 (2006.01)

Patent

CA 2163887

Acetals of podophyllotoxin- .beta.-D-glucopyranoside or of 4'-demthylpodophyllotoxin-.beta.- D- glucopyranoside having general formula a) wherein R is OH or OCH3, and R' is an alkyl, aryl or heterocyclic residue, are used for the preparation of a pharmaceutical composition for the treatment or prophylaxis of states of amyloidosis.

Acétals de podophyllotoxin- beta -D-glucopyranoside ou de 4'-déméthylpodophyllotoxin- beta -D-glucopyranoside répondant à la formule générale (I), dans laquelle R représente OH ou OCH3, et R' représente un reste hétérocyclique, alkyle ou aryle. Ces acétals sont utilisés pour la préparation d'une composition pharmaceutique destinée au traitement ou à la prophylaxie d'états pathologiques associés à l'amyloïdose.

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