A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/45 (2006.01)
Patent
CA 2548016
The present invention relates to LIMK-1, a LIMK-1-analogue or LIMK-1 ligand for the binding to GPIIb and/or activation or inhibition of GPIIb/Illa downstream signaling, for the production of a medicament for the prevention or treatment of a thrombus formation or blood clotting disease, methods of screening a LIMK-1 analogue or a LIMK-1 ligand and a method for producing a medicament for the treatment of a thrombus formation or blood clotting disease.
La présente invention a trait à l'utilisation de LIMK-1, un analogue de LIMK-1 ou un ligand de LIMK-1 pour la liaison à la glycoprotéine la glycoprotéine II et/ou l'activation ou l'inhibition de la signalisation en aval de la glycoprotéine IIb/Illa, pour la production d'un médicament pour la prévention d'une formation de thrombus ou d'une maladie de coagulation sanguine, à des procédés de criblage d'un analogue de LIMK-1 ou d'un ligand de LIMK-1 et à un procédé pour la production d'un médicament pour le traitement d'une formation de thrombus ou d'une maladie de coagulation sanguine.
Herrmann Matthias
Leeuw Thomas
Rueck Alexander
Sibenhorn Gertrud
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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