Use of long-chain n-alkyl derivatives of deoxynojirimycin...

Details Use of long-chain n-alkyl derivatives of deoxynojirimycin... Use of long-chain n-alkyl derivatives of deoxynojirimycin...

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2352544

A novel method is disclosed for the treatment of a patient affected with Gaucher's disease or other such glycolipid storage diseases. The method comprises administering to said patient a therapeutically effective amount of a long-chain N-alkyl derivative of deoxynojirimycin to alleviate or inhibit the glycolipid storage disease. The long-chain alkyl group has from nine to about 20 carbon atoms and preferably is nonyl or decyl.

L'invention concerne un procédé de traitement de la maladie de Gaucher ou autre maladie liée au stockage des glycolipides, qui consiste à administrer une quantité thérapeutiquement efficace de dérivé N-alkyle à chaîne longue de désoxynojirimycine pour atténuer ou inhiber le stockage des glycolipides. Le groupe alkyle à chaîne longue comprend entre 9 et environ 20 atomes de carbone, et il s'agit de préférence de nonyle ou de décyle.

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