Use of low molecular weight thrombin inhibitors in...

A - Human Necessities – 61 – K

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A61K 38/05 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2517191

According to the invention there is provided the use of a low molecular weight thrombin inhibitor, or a pharmaceutically acceptable derivative thereof, for the manufacture of a medicament for use in cholesterol-lowering therapy and/or modification of lipid (triglyceride), lipoprotein, and apolipoprotein, profiles associated with an increased risk of cardiovascular complications.

L'invention concerne l'utilisation d'un inhibiteur de thrombine de faible poids moléculaire ou d'un dérivé pharmaceutiquement acceptable de cet inhibiteur pour la fabrication d'un médicament destiné à être utilisé dans un traitement hypocholestérolémiant et/ou une modification des profils lipidiques (triglycéridiques), lipoprotéiques et apolipoptoréiques associés à un risque accru de complications cardiovasculaires.

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