A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 16/24 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2267069
There is disclosed a method of treating or preventing a disease which involves cell overproliferation in a subject comprising administering to a subject in which such treatment or prevention is desired a therapeutically effective amount of a MIF (macrophage migration inhibitory factor) antagonist agent. There is further disclosed a method for treating tumor neovascularization in a subject, comprising administering to a subject a therapeutically effective amount of an agent which inhibits or neutralizes migration inhibitory factor (MIF) activity.
Cette invention concerne un procédé de traitement ou de prévention des maladies liées à une surprolifération cellulaire chez un sujet, consistant à administrer au sujet pour lequel le traitement ou la prévention est souhaité, une dose thérapeutiquement efficace d'un agent antagoniste de MIF (facteur d'inhibition de la migration des macrophages). Elle concerne également un procédé de traitement de la néovascularisation tumorale chez un sujet qui consiste à administrer à ce sujet, une dose thérapeutiquement efficace d'un agent inhibant ou neutralisant l'activité de MIF.
Bucala Richard J.
Chesney Jason A.
Baxter Healthcare Sa
Baxter International Inc.
Smart & Biggar
The Picower Institute For Medical Research
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