Use of meganucleases for inducing homologous recombination...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/90 (2006.01) A01K 67/027 (2006.01) A61K 38/46 (2006.01) C12N 9/22 (2006.01) C12N 15/55 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2514517

Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and to its application for genome engineering and gene therapy.

L'invention concerne l'utilisation de méganucléases pour induire une recombinaison homologue ex vivo et in toto dans des tissus somatiques de vertébré ainsi que l'application de cette utilisation à des fins d'ingénierie génomique et de thérapie génique.

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