Use of methylene amide derivatives in cardiovascular disorders

Details Use of methylene amide derivatives in cardiovascular disorders Use of methylene amide derivatives in cardiovascular disorders

A - Human Necessities

61

K

A61K 31/197 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2554919

The present invention is related to the use of substituted methylene amide derivatives of Formula (I) for the treatment and/or prevention of cardiovascular disorders such as coronary obstruction and heart failure. In particular, the present invention is related to the use of substituted methylene amide derivatives of Formula (I) in particular for the treatment and/or prevention of endothelial dysfunction in heart failure.

La présente invention concerne l'utilisation de dérivés substitués de méthylène amides correspondant à la formule (I) pour le traitement et/ou la prévention de troubles cardio-vasculaires tels que l'obstruction coronaire et l'insuffisance cardiaque. La présente invention concerne notamment l'utilisation de dérivés substitués de méthylène amide correspondant à la formule (I), notamment dans le traitement et/ou la prévention du dysfonctionnement endothélial lors de l'insuffisance cardiaque.

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