Use of methylene blue and related compounds to prevent or...

Details Use of methylene blue and related compounds to prevent or... Use of methylene blue and related compounds to prevent or...

A - Human Necessities

61

K

A61K 31/5415 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2424000

The present invention relates to the use of the dye methylene blue (MB) or a related compound to prevent or reverse an exaggerated hemodynamic reaction in animals in need thereof, including humans. More specifically, the present invention concerns the use of MB or a related compound to prevent or reverse hypotension, unstable angina, myocardial infarction or shock caused by the concomitant ingestion of a phosphodiesterase inhibitor, such as sildenafil citrate, and a NO-donor, such as L- arginine, or an organic nitrate, such as nitroglycerin.

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