Use of methylnaltrexone to treat immune suppression

Details Use of methylnaltrexone to treat immune suppression Use of methylnaltrexone to treat immune suppression

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/00 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2449175

Methods for treating opioid-induced immune suppression with peripheral opioid antagonists are provided. In one embodiment, the method involves administering methylnaltrexone. Pharmaceutical compositions comprising an opioid, an opioid antagonist, and a pharmaceutical agent are also provided.

L'invention se rapporte à des procédés de traitement de l'immunodépression provoquée par des opioïdes au moyen d'antagonistes des opioïdes périphériques. Selon un mode de réalisation, le procédé consiste à administrer de la méthylnaltrexone. L'invention a également trait à des compositions pharmaceutiques comprenant un opioïde, un antagoniste des opioïdes et un agent pharmaceutique.

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