A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/14 (2006.01) A61K 35/18 (2006.01) A61K 38/13 (2006.01) A61K 41/00 (2006.01) A61K 51/12 (2006.01) C12N 13/00 (2006.01) C12N 15/01 (2006.01) A61K 35/12 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2162732
The invention provides a modified human cytotoxic T cell line, which is characterized by dual activity in vitro and in vivo against tumor cells and virus-infected cells. Also provided are effective and safe methods for use of the modified cells in adoptive therapy of cancer and untreatable viral diseases in MHC-mismatched recipients, and in marrow purging to achieve complete eradication of residual tumor cells from marrows of patients with leukemia and other types of cancer. Also provided are effective and safe methods for use of the modified cells in the manufacture of a veterinary composition for adoptive therapy of canine lymphoma and feline leukemias.
Cesano Alessandra
Rovera Giovanni
Santoli Daniela
Finlayson & Singlehurst
The Wistar Institute Of Anatomy And Biology
LandOfFree
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