Use of mycobacterium .alpha. antigen to prevent or treat...

Details Use of mycobacterium .alpha. antigen to prevent or treat... Use of mycobacterium .alpha. antigen to prevent or treat...

A - Human Necessities

61

K

A61K 39/04 (2006.01) A61K 31/711 (2006.01) A61P 11/06 (2006.01) A61P 27/00 (2006.01) A61P 27/16 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2443502

Because of inhibiting the production of interleukin-4, etc., ameliorating the TH2-type cytokine-predominant immune state and relieving symptoms of allergic diseases such as IgE production, histamine release and eosinophilic infiltration, a gene encoding an .alpha. antigen and an .alpha. antigen protein are highly efficacious in preventing and treating atopic diseases (atopic dermatitis, asthma, allergic rhinitis, allergic conjunctivitis, etc.) and, in a broader sense, other allergic diseases.

Du fait qu'ils inhibent la production d'interleukine-4, entre autres, qu'ils améliorent l'état du système immunitaire à prédominance de la cytokine du type TH2 et qu'ils soulagent les symptômes des maladies allergiques tels que la production d'IgE, la libération d'histamine et l'infiltration éosinophile, un gène codant un antigène alpha et une protéine d'antigène alpha sont extrêmement efficaces pour prévenir et traiter les maladies atopiques (la dermatite atopique, l'asthme, la rhinite allergique, la conjonctivite allergique et autres) et, de manière plus générale, d'autres maladies allergiques.

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