Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid...

Details Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid... Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid...

A - Human Necessities

61

K

A61K 31/44 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2170285

The present invention relates to the use of N-alkylated 1,4-dihydropyridinecarboxylic acid esters of the general formula (I), Image (I) some of which are known and in which R1 to R6 have the meanings given in the description, as anti- atherosclerotic medicaments, in particular to their use for the prophylaxis of restenoses following angioplasties s and vascular surgery.

L'invention concerne l'utilisation comme médicaments anti-athérosclérose, d'esters d'acide 1-4-dihydropyridin dicarboxylique N-alkylés partiellement connus de la formule (I), dans laquelle R<1> à R<6> ont la notation mentionnée dans la description. L'invention concerne notamment leur utilisation pour assurer la prophylaxie de la resténose après des angioplasties et des interventions chirurgicales vasculaires.

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