Use of n-methyl bases of ethanolamine for prevention of cell...

A - Human Necessities – 61 – K

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A61K 31/00 (2006.01) A61K 31/131 (2006.01)

Patent

CA 2378482

N-monomethylethanolamine, N,N'-dimethylethanolamine and mixtures thereof are useful for preventing cell death induced by oxidative stress, in particular for protecting brain tissue from ischemic stroke and for the alleviation of ischemic stroke, thromboembolic or hemorrhagic stroke, cardiac arrest, oxidative distressed pregnancy and neurodegenerative disorders such as aging and Alzheimer's disease.

L'invention concerne un groupe N-monométhyléthanolamine et N,N'-diméthyléthanolamine et des mélanges de ceux-ci utilisés pour prévenir la mort cellulaire induite par le stress oxydant, en particulier pour protéger les tissus cérébraux des accidents ischémiques cérébraux et pour alléger les souffrances induites par des accidents ischémiques cérébraux, des attaques d'apoplexie thromboemboliques ou hémorragiques, des arrêts cardiaques, des grossesses à trouble oxydatif et des troubles neurodégénératifs tels que le vieillissement et la maladie d'Alzheimer.

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