Use of n-myristoyltransferase on non-tumor tissue for cancer...

Details Use of n-myristoyltransferase on non-tumor tissue for cancer... Use of n-myristoyltransferase on non-tumor tissue for cancer...

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01) C12Q 1/04 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2623653

A diagnostic method and kit are disclosed for detection of cancer. Detection of elevated levels of N-myristoyltransferase (NMT) or NMT activity in blood or bone marrow, and specifically in peripheral blood mononuclear cells, can be used as a marker for cancer. The use of this method for detection of adenocarcinoma, such as colorectal cancer, is exemplified.

L'invention concerne une méthode et une trousse de diagnostic pour la détection d'un cancer. La détection de taux élevés de N-myristoyltransférase (NMT) ou d'une activité NMT dans le sang ou la moelle épinière, et notamment dans les cellules mononucléaires du sang périphérique, peut être utilisée comme marqueur pour un cancer. L'utilisation de cette méthode pour la détection d'un adénocarcinome, tel que le cancer colorectal, est exemplifiée.

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