Use of n,n-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine...

Details Use of n,n-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine... Use of n,n-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine...

A - Human Necessities

61

K

A61K 31/138 (2006.01) A61K 31/704 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2473024

The present invention provides for the use of N,N-diethyl-2-[-4-(phenylmethyl)- phenoxy]ethanamine monohydrochloride (DPPE) in cancer therapy. DPPE is used in the treatment of patients having, or suspected of having, an aggressive cancer. The present invention further provides for the use of DPPE in the treatment of a patient suspected of having an existing cancer, wherein the use follows a surgery for treatment of a primary cancer that is estrogen-receptor negative. Also provided are pharmaceutical compositions comprising DPPE for use in the treatment of patients having, or suspected of having, an aggressive cancer and pharmaceutical kits comprising such compositions.

L'invention concerne l'utilisation de N,N-diethyl-2-[-4-(phenylmethyl)-phenoxy]ethanamine monohydrochloride (DPPE) dans la thérapie du cancer. On utilise DPPE pour traiter des patients suspectés ou souffrant d'un cancer agressif. L'invention concerne également l'utilisation de DPPE pour traiter un patient suspecté de l'existence d'un cancer, cette utilisation faisant suite à une chirurgie destinée à traiter un cancer primaire qui est oestrogène récepteur négatif. L'invention concerne enfin des compositions pharmaceutiques comprenant DPPE utilisées pour traiter des patients suspectés ou souffrant d'un cancer agressif et des kits pharmaceutiques comprenant lesdites compositions.

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